On the Elimination of the 3-Benzylthioenol Ether of Pregn-4-ene-3,20-dione by W-2 Raney Nickel
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چکیده
Reaction of 3-benzylthiopregna-3,5-dien-20-one or of pregna-3,5-dien-20-one with W-2 Raney nickel in acetone afforded a mixture of 20-ketopregnanes with different degrees of insaturation on rings A and B, of which the main component was identified as pregn-2-en-20-one. When deactivated Raney nickel was used, the main product was the expected pregna-3,5-dien-20-one with minor amounts of pregn-4-en-20-one and pregn-5-en-20-one.
منابع مشابه
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dione); 1 1flOH-P (1 1/?-hydroxyprogesterone; 1 1 /?-hydroxypregn-4ene-3,20-dione); 1 I-0x0-P (1 1-oxoprogesterone; pregn-4-ene-3,11,20trione); 21-d-F (2 I-deoxycortisol; 11/?,17a-dihydroxypregn-4-ene-3,20dione); 2 1 -d-E (2 1-deoxycortisone; 17a-hydroxypregn-4-ene-3,11,20trione); 1 1-deoxycortisol (Reichstein’s substance S ; cortexolone; 1 7 ~ 2 l-dihydroxypregn-4-ene-3,20-dione); DHS (dihydro...
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تاریخ انتشار 2012